Transformation of preclinical study results into clinical applications: Improving protocols and clinical practice in translational orthopaedics

I-7: Introducing Blastocyst Culture and Transfer into Clinical Practice

Translational applications of flow cytometry in clinical practice.

Flow cytometry has evolved over the past 30 y from a niche laboratory technique to a routine tool used by clinical pathologists and immunologists for diagnosis and monitoring of patients with cancer and immune deficiencies. Identification of novel patterns of expressed Ags has led to the recognition of cancers with unique pathophysiologies and treatment strategies. FACS had permitted the isolat...

The discovery of rivaroxaban: translating preclinical assessments into clinical practice

Direct oral anticoagulants that target a single coagulation factor (such as factor Xa or thrombin) have been developed in recent years in an attempt to address some of the limitations of traditional anticoagulants. Rivaroxaban is an oral, direct factor Xa inhibitor that inhibits free and clot-bound factor Xa and factor Xa in the prothrombinase complex. Preclinical studies demonstrated a potent ...

The Influential Factors in Profiting the Research Evidences and Results in Clinical Practice by Rehabilitation Practitioners

Objective: This study intends to determine the factors attributed to the use of research evidences results in practice, by rehabilitation’s practitioners in educational hospitals of Tehran. Materials & Methods: In this study, the research community included all the 485 rehabilitation practitioners working in educational hospitals of Tehran. The samples were consisted of 165 persons which hav...

Metabolomics in toxicology: preclinical and clinical applications.

Metabolomics first burst into the toxicology arena approximately 10–12 years ago, experiencing rapid growth as a science in the intervening period (Fig. 1). Though metabolomics still trails the publication rates of its sister technologies, genomics and proteomics, it is closing the gap in terms of both the numbers of publications and the quality of those publications. One continuing source of c...